Guyanese Matthew Nandu and Isai Thorne made contributions on Tuesday, but West Indies Under-19s were defeated by England Under-19s in the fifth Youth ODI in Canterbury.
The one-wicket victory gave the English youngsters a 4-1 series lead with one game to play on Friday.
Batting first, West Indies made 166 all out in 41 overs with 18-year-old Nandu topscoring with 51. The right-handed opener struck three fours in his 58-ball knock.
Skipper Giovonte Depeiza made 34 not out and Ackeem Auguste 32, as Joshua Boyden (2-21), Fateh Singh (2-24) and Nathan Barnwell (2-25) were among the wickets.
England lost wickets at regular intervals, but managed to sneak home at 170-9 in 42 overs. George Bell led the run-chase with 60 not out, while James Cole made 31 and Rehan Ahmed 27.
Bowling for West Indies Under-19s, Andel Gordon took 3-37, Johann Layne 3-40 and Thorne 2-41.
Match schedule and results
Saturday, September 4: 1st Youth ODI – England won by 166 runs at Beckenham
Monday, September 6: 2nd Youth – England won by one wicket at Beckenham
Wednesday, September 8: 3rd Youth ODI – West Indies won by two wickets at Beckenham
Friday, September 10: 4th Youth ODI – England won by nine wickets at Canterbury
Tuesday, September 14: 5th Youth ODI – England won by one wicket at Canterbury
Friday, September 17: 6th Youth ODI – Canterbury